A Consanguinity Related Autosomal Translocation which Leads to Premature Ovarian Failure.

A de novo Reciprocal X; 9 Translocation in A Patient with Premature Ovarian Failure

Inm-7: Genetic Etiologies of Premature Ovarian Failure

Premature Ovarian Failure (POF) defined as functional stop of ovaries before the age of 40. It is a common cause of infertility in women that characterized by primary or secondary amenorrhea, high gonadotropin levels and estrogen level declining in patients. Factors that reduce follicle or defect in the follicle growth stimulating mechanism defined as numerous complication factors that they can...

Premature ovarian failure in a woman with a balanced 15;21 translocation: a case report

INTRODUCTION A case of premature ovarian failure with concomitant findings of Robertsonian translocation between 15 and 21 chromosomes is reported here. The aforementioned karyotypic aberration has not been reported in the context of premature ovarian failure to date. CASE PRESENTATION We present a case of premature ovarian failure in a 27-year-old infertile Kurdish Iranian woman with a Rober...

I-36: The Necessity of Genetic Screening in Premature Ovarian Failure and Diminished Ovarian Reserved Patients

Variability in the subfertile patient population excludes the possibility of a single approach to controlled ovarian stimulation (COS) covering all the requirements of a patient. Modern medical science has made great advances in the understanding and the development of new drugs, treatment options and quantitative methods that can identify single patient characteristics. Factors that reduce fol...

I-41: Genetic Causes of Premature Ovarian Failure (POF) and early Menopause

Premature ovarian failure (POF) is a heterogeneous disorder, defined as menopause under age 40 years. The prevalence is 1%; POF before age 30 years is much less common. Chromosomal causes have long been recognized - visible deletions of the X chromosome, 45,X/46,XX mosaicism, and autosomal rearrangements (balanced translocations). Toxins or iatrogenic causes (e.g., chemotherapeutic agents) are ...